AnaptysBio is a clinical-stage biotechnology company focused on delivering innovative immunology therapeutics. It is developing immune cell modulators, including two checkpoint agonists in clinical-stage development, for autoimmune and inflammatory disease: rosnilimab, its PD-1 agonist, in a planned Phase 2b trial for the treatment of moderate-to-severe rheumatoid arthritis; and ANB032, its BTLA agonist, currently in a Phase 2b trial for the treatment of moderate-to-severe atopic dermatitis. Its preclinical immune cell modulator portfolio includes ANB033, an anti-CD122 antagonist antibody for the treatment of autoimmune and inflammatory diseases.
In addition, AnaptysBio has developed two cytokine antagonists available for out-licensing: imsidolimab, an anti-IL-36R antagonist, in Phase 3 for the treatment of generalized pustular psoriasis, or GPP, and etokimab, an anti-IL-33 antagonist for the treatment of respiratory disorders that is Phase 2/3 ready. AnaptysBio has also discovered multiple therapeutic antibodies licensed to GSK in a financial collaboration for immune-oncology, including an anti-PD-1 antagonist antibody (JEMPERLI (dostarlimab-gxly)), an anti-TIM-3 antagonist antibody (cobolimab, GSK4069889) and an anti-LAG-3 antagonist antibody (GSK4074386).
Enable broad development of our immune cell modulator portfolio, including our checkpoint agonist programs, rosnilimab and ANB032, in indications including moderate-to-severe RA and AD, respectively.
Generate in vitro and in vivo translational and clinical data to inform the potential differentiation of our molecules from in-class competitors and, relative to standard of care, treat patient populations most likely to have deeper and/or more durable responses by restoring immune balance.
Facilitate the global commercialization of our checkpoint agonists while retaining rights in key therapeutic areas and/or commercial markets to enable us to become a fully integrated discovery, development and commercial organization.
Continue to leverage our research platform to generate potentially best-in-class antibodies against high-value immunological targets.
Maximize return on equity through execution against a multi-year capital and operating plan, including the potential for future royalty revenues from our GSK immuno-oncology collaboration and, where actionable, monetizing our legacy cytokine antagonist programs and enabling further external development and, potentially, commercialization.
Senior Leadership Team
Angela Stambaugh
Vice President, Program Management
Ben Stone
Senior Vice President, Corporate Development
Beth Mueller
Senior Vice President, Human Resources
Daniel Faga
Interim President & CEO
Dennis Mulroy
Chief Financial Officer
Eric Loumeau
Chief Legal Officer
Kenneth Luu, Ph.D.
Vice President, Clinical Pharmacology
Lewis Gryziewicz, PharmD
Vice President, Regulatory Affairs
Martin Dahl, Ph.D.
Senior Vice President, Research
Paul F. Lizzul, M.D., Ph.D., M.P.H, M.B.A.
Chief Medical Officer
Pejman Soroosh, Ph.D.
Vice President, Immunology
Priya Raina
Vice President, Clinical Operations
Stephen Parmley, Ph.D.
Vice President, Target BiologySpotlight on Medical & Clinical Development Expertise
Bruce Randazzo, M.D., Ph.D., FAAD
Vice President, Clinical Development
Cailin Sibley, M.D., MHS, FACR
Vice President, Translational Medicine
Jocelyne Papacharalambous, M.D., MPH
Executive Medical Director, Medical DevelopmentBoard Of Directors
Daniel Faga
Interim President & CEOMr. Faga is a seasoned executive with more than 20 years of industry and advisory experience in the life sciences industry. Most recently, he was the chief operating officer at Mirati Therapeutics responsible for leading the company’s strategy, corporate finance, legal and other business operations.
+Dennis Fenton, Ph.D.
Former Executive Vice President, AmgenDr. Fenton held positions of increasing responsibility at Amgen from 1982 through to his retirement in 2008, including Vice President of Research, Senior Vice President of Sales and Marketing, Senior Vice President of Operations and Executive Vice President.
+Rita Jain, M.D.
Former Executive Vice President and Chief Medical Officer of ChemoCentryxRita Jain, M.D., joined our Board of Directors in April 2023. Dr. Jain is a rheumatologist and currently serves on the Board of Directors of Provention Bio, Inc. and Celldex Therapeutics, and serves on the supervisory board of AM Pharma.
+Magda Marquet, Ph.D.
Co-founder of Althea Technologies, AltheaDx and ALMA Life Sciences, LLCDr. Magda Marquet joined our Board of Directors in January 2021. She was the co-CEO of Althea Technologies from 2000 to 2008. She is currently the co-CEO of Alma Life Sciences. LLC, an investment and consulting firm and serves on several Boards of Directors.
+Oleg Nodelman
Founder and Portfolio Manager of EcoR1 Capital LLCOleg Nodelman joined our Board of Directors in April 2021. He is the Founder and Portfolio Manager of EcoR1 Capital LLC, a biotech-focused investment advisory firm established in 2013, and has nearly twenty years of experience in biotech investing.
+Hollings Renton
Former President and CEO of Onyx PharmaceuticalsHollings Renton has previously served as the Chief Executive Officer and President of Onyx Pharmaceuticals from 1993 to 2008 and as the Chairman of the Board from 2000 to 2008.
+John Schmid
Former CFO of Auspex PharmaceuticalsJohn Schmid has over 35 years of experience in financial and senior management in the biotech industry and has raised over $900 million in private and public equity as well debt financings as a Chief Financial Officer.
+James N. Topper, M.D., Ph.D.
Chairman of AnaptysBio Managing General Partner at Frazier HealthcareJamie Topper, M.D., Ph.D., is a Managing General Partner of Frazier Healthcare Partner’s Life Sciences team. He joined Frazier in 2003 and opened Frazier’s Menlo Park office in the same year. Throughout his 11 years as a General Partner, Dr. Topper has invested across over 20 companies encompassing a broad spectrum of Life Science and Biopharmaceutical companies.
+J. Anthony Ware, M.D.
Former SVP Product Development, Lilly Bio-Medicines, Eli Lilly and CompanyDr. Ware served as the Senior Vice President of Product Development of Lilly Bio-Medicines at Eli Lilly and Company, where he was responsible for the clinical development and regulatory approval of new medicines in multiple therapeutic areas.
+Scientific Advisory Board
Michael Gallatin, Ph.D.
Former Vice President and Scientific Director of ICOS CorporationMichael Gallatin, Ph.D., is a former Vice President and Scientific Director of ICOS Corporation, where his responsibilities included discovery, preclinical research, medicinal chemistry and process chemistry groups, including those responsible for worldwide development and launch of Tadalafil (Cialis®).
+Christopher Hunter, Ph.D.
Mindy Halikman Heyer President’s Distinguished Chair and former chair of the Department of Pathobiology at the University of Pennsylvania School of Veterinary MedicineChristopher Hunter, Ph.D. is the Mindy Halikman Heyer President’s Distinguished Chair and former chair of the Department of Pathobiology at the University of Pennsylvania School of Veterinary Medicine. Dr. Hunter’s research has focused on the host’s immune response to infections and the innate events that lead to the development of long term protective immunity mediated […]
+John G. Monroe, Ph.D.
Emeritus Professor, University of Pennsylvania School of MedicineJohn G. Monroe, Ph.D., is an Emeritus Professor at the Perelman School of Medicine at the University of Pennsylvania. He is a former Senior Director at Genentech where he led the Immunology Discovery Department that is responsible for new target discovery and pre-clinical validation.
+Luisa Salter-Cid, PH.D.
Chief Scientific Officer, Pioneering Medicines and Board Member Jounce TherapeuticsLuisa Salter-Cid, Ph.D. is the current Chief Scientific Officer at Pioneering Medicines, Flagship Pioneering and has been serving on the board of directors for Jounce Therapeutics since February 2021. Throughout her career Dr. Salter-Cid has authored of over 70 publications and patents.
+Contact
AnaptysBio, Inc.
10770 Wateridge Circle
Suite 210
San Diego, CA 92121-5801
Phone: (858) 362-6295
Fax: (858) 362-6296
info@anaptysbio.com
General Information
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