TESARO Partnership

Under our immuno-oncology collaboration with TESARO, we have granted exclusive rights to TESARO to develop and commercialize the following AnaptysBio-generated antibody product candidates:

  • Anti-PD-1 Monospecific Antagonist Antibody (TSR-042): Phase 1 clinical trial dosing initiated in the first quarter of 2016 subsequent to the acceptance of a U.S. FDA IND, finalize registration strategy and initiate a registration program in H1 2017;

  • Anti-TIM-3 Monospecific Antagonist Antibody (TSR-022): Phase 1 clinical trial dosing initiated in the third quarter of 2016 subsequent to the acceptance of a U.S. FDA IND, expect initiation of an anti-PD-1 combination trial in mid-2017;

  • Anti-LAG-3 Monospecific Antagonist Antibody (TSR-033): currently in preclinical development, expect the initiation of a Phase 1 trial in Q2 2017;

  • Anti-PD-1/TIM-3 Bispecific Antagonist Antibody: currently in lead selection process;

  • Anti-PD-1/LAG-3 Bispecific Antagonist Antibody: lead candidate identified; and

  • Undisclosed Bispecific Antagonist Antibody: currently in lead selection process.

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